TAS2R42

Taste receptor, type 2, member 42 is a protein that in humans is encoded by the TAS2R42 gene.

Protein-coding gene in the species Homo sapiens

TAS2R42
Identifiers
Aliases	TAS2R42, T2R24, T2R42, T2R55, TAS2R55, taste 2 receptor member 42
External IDs	OMIM: 613966; MGI: 2681280; HomoloGene: 52298; GeneCards: TAS2R42; OMA:TAS2R42 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12p13.2 Start 11,185,993 bp[1] End 11,186,937 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6 G1|6 64.03 cM Start 132,933,847 bp[2] End 132,934,882 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle tonsil superior frontal gyrus ganglionic eminence renal cortex myeloid leukocyte monocyte duodenum lymph node islet of Langerhans n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity bitter taste receptor activity Cellular component integral component of membrane plasma membrane membrane Biological process detection of chemical stimulus involved in sensory perception of bitter taste signal transduction response to stimulus sensory perception of taste G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 353164 387356 Ensembl ENSG00000273505 ENSG00000186136 ENSMUSG00000057699 UniProt Q7RTR8 Q7M708 RefSeq (mRNA) NM_181429 NM_207030 RefSeq (protein) NP_852094 NP_996913 Location (UCSC) Chr 12: 11.19 – 11.19 Mb Chr 6: 132.93 – 132.93 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Taste receptor, type 2, member 42 is a protein that in humans is encoded by the TAS2R42 gene.^[5][6]

References

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1. ^ ^{a b c} ENSG00000186136 GRCh38: Ensembl release 89: ENSG00000273505, ENSG00000186136 – Ensembl, May 2017
2. ^ ^{a b c} GRCm38: Ensembl release 89: ENSMUSG00000057699 – Ensembl, May 2017
3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ "Entrez Gene: taste receptor".
6. ^ Shi P, Zhang J, Yang H, Zhang YP (May 2003). "Adaptive diversification of bitter taste receptor genes in Mammalian evolution". Mol. Biol. Evol. 20 (5): 805–14. doi:10.1093/molbev/msg083. PMID 12679530.

Further reading

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• Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes". Mol. Biol. Evol. 22 (3): 432–6. doi:10.1093/molbev/msi027. PMID 15496549.
• Go Y, Satta Y, Takenaka O, Takahata N (2005). "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates". Genetics. 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMC 1449719. PMID 15744053.

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