Clorprenaline

Clorprenaline
Clinical data
Other names	Chlorprenaline; Isoprophenamine; Compound 20025; L-20025; 2-Chloro-β-hydroxy-N-isopropylphenethylamine
Drug class	Sympathomimetic; Bronchodilator; Sympathomimetic
Identifiers
	IUPAC name 1-(2-chlorophenyl)-2-(propan-2-ylamino)ethanol;
CAS Number	3811-25-4 ; 5588-22-7 (hydrochloride);
PubChem CID	2810;
ChemSpider	2708;
UNII	3W4327W76O;
KEGG	D01835;
ChEBI	CHEBI:146226;
ChEMBL	ChEMBL1902627;
CompTox Dashboard (EPA)	DTXSID3048316 ;
ECHA InfoCard	100.021.175
Chemical and physical data
Formula	C11H16ClNO
Molar mass	213.71 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C)NCC(C1=CC=CC=C1Cl)O;
	InChI InChI=1S/C11H16ClNO/c1-8(2)13-7-11(14)9-5-3-4-6-10(9)12/h3-6,8,11,13-14H,7H2,1-2H3; Key:SSMSBSWKLKKXGG-UHFFFAOYSA-N;

Clorprenaline (INNTooltip International Nonproprietary Name, USANTooltip United States Adopted Name, BANTooltip British Approved Name), also known as isoprophenamine and known as clorprenaline hydrochloride (USANTooltip United States Adopted Name, JANTooltip Japanese Accepted Name) in the case of the hydrochloride salt, is a sympathomimetic and bronchodilator medication which is marketed in Japan.^[1]^[2]^[3] It acts as a β-adrenergic receptor agonist or as a β-sympathomimetic.^[2]^[3] Brand names of clorprenaline in Japan are numerous and include Asnormal, Bazarl, Bronchon, Clopinerin, Conselt, Cosmoline, Fusca, Kalutein, Pentadoll, Restanolon, and Troberin.^[2]^[1] The drug was first described in the literature by 1956.^[1]^[4]

References

^ ^a ^b ^c Elks J (2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. p. 305. ISBN 978-1-4757-2085-3. Retrieved 17 October 2024.
^ ^a ^b ^c Schweizerischer Apotheker-Verein (2004). Index Nominum: International Drug Directory. Medpharm Scientific Publishers. p. 309. ISBN 978-3-88763-101-7. Retrieved 17 October 2024.
^ ^a ^b Morton IK, Hall JM (2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Netherlands. p. 80. ISBN 978-94-011-4439-1. Retrieved 17 October 2024.
^ Gibson WR, Powell CE, Swanson EE (December 1956). "The pharmacological action of 1-o-chlorophenyl-2-isopropylaminoethanol (isoprophenamine); a bronchodilator". J Am Pharm Assoc. 45 (12): 785–787. doi:10.1002/jps.3030451205. PMID 13376372.

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[Elks2014-1] Elks J (2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. p. 305. ISBN 978-1-4757-2085-3. Retrieved 17 October 2024.

[IndexNominum2004-2] Schweizerischer Apotheker-Verein (2004). Index Nominum: International Drug Directory. Medpharm Scientific Publishers. p. 309. ISBN 978-3-88763-101-7. Retrieved 17 October 2024.

[MortonHall2012-3] Morton IK, Hall JM (2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Netherlands. p. 80. ISBN 978-94-011-4439-1. Retrieved 17 October 2024.

[GibsonPowellSwanson-4] Gibson WR, Powell CE, Swanson EE (December 1956). "The pharmacological action of 1-o-chlorophenyl-2-isopropylaminoethanol (isoprophenamine); a bronchodilator". J Am Pharm Assoc. 45 (12): 785–787. doi:10.1002/jps.3030451205. PMID 13376372.

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