BIDN
BIDN is an insecticide with a structure related to norbornane. It functions as a GABA receptor antagonist and convulsant.
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| Names | |
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| IUPAC name
3,3-Bis(trifluoromethyl)bicyclo[2.2.1]heptane-2,2-dicarbonitrile
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| Other names
Flucybene
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| Identifiers | |
3D model (JSmol)
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| ChemSpider | |
PubChem CID
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CompTox Dashboard (EPA)
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| Properties | |
| C11H8F6N2 | |
| Molar mass | 282.189 g·mol−1 |
| Hazards | |
| GHS labelling: | |
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| Danger | |
| H300 | |
| P264, P270, P301+P310, P321, P330, P405, P501 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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BIDN is an insecticide with a structure related to norbornane. It functions as a GABA receptor antagonist and convulsant.[1]
Further reading
[edit]- Chen, Ligong; Durkin, Kathleen A.; Casida, John E. (2006). "Structural model for γ-aminobutyric acid receptor noncompetitive antagonist binding: Widely diverse structures fit the same site". Proceedings of the National Academy of Sciences. 103 (13): 5185–5190. doi:10.1073/pnas.0600370103. PMC 1458815. PMID 16537435.
- Zhao, Chunqing; Hwang, Sung Hee; Buchholz, Bruce A.; Carpenter, Timothy S.; Lightstone, Felice C.; Yang, Jun; Hammock, Bruce D.; Casida, John E. (2014). "GABAAreceptor target of tetramethylenedisulfotetramine". Proceedings of the National Academy of Sciences. 111 (23): 8607–8612. doi:10.1073/pnas.1407379111. PMC 4060666. PMID 24912155.
See also
[edit]References
[edit]- ^ Rauh, James J; Holyoke, Caleb W; Kleier, Daniel A; Presnail, James K; Benner, Eric A; Cordova, Daniel; Howard, Michael H; Hosie, Alastair M; Buckingham, Steven D; Baylis, Howard A; Sattelle, David B (1997). "Polycyclic dinitriles: a novel class of potent GABAergic insecticides provides a new radioligand, [3H]BIDN". Invertebrate Neuroscience. 3 (2–3): 261–8. doi:10.1007/bf02480383. PMID 9783448. S2CID 33478021.
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